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Search Results for " igf-i receptor "

2

抑制剂 & 化合物

7

重组蛋白

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Cat. No.	Product Name	Target	Signaling Pathways
T70568	H-1356
	H-1356 is an insulin-like growth factor 1(IGF-I) analog that inhibits autophosphorylation of IGF-I receptor.
T69221	BMS-554417
	BMS-554417 is a novel inhibitor of IGF-IR, which inhibits IGF-IR and insulin receptor kinase activity and proliferation in vitro, and reduces tumor xenograft size in vivo. In a series of carcinoma cell lines, the IC50 for proliferation ranged from 120 nmol/L (Colo205) to >8.5 micromol/L (OV202). BMS-554417 treatment inhibited IGF-IR and insulin receptor signaling through extracellular signal-related kinase as well as the phosphoinositide 3-kinase/Akt pathway, as evidenced by decreased Akt phosph...

化合物

Cat.No: T70568

Cat.No: T69221

Species：

Expression System：

Tag：

Cat. No.	Product Name	Species	Expression System
TMPY-00834	IGF1R/CD221 Protein, Human, Recombinant (His) IGF-I R,IGFR,	Human	HEK293 Cells
	IGF1R/CD221 Protein, Human, Recombinant (His) is expressed in HEK293 mammalian cells with His tag. The predicted molecular weight is 81 kDa and the accession number is P08069.
TMPK-00456	IGF1R/CD221 Protein, Human, Recombinant (aa 31-932, His & Avi), Biotinylated CD221,MGC142172,IGFIR,I	Human	HEK293 Cells
	The type 1 IGF receptor (IGF1R) is a transmembrane tyrosine kinase that is frequently overexpressed by tumours, and mediates proliferation and apoptosis protection. IGF signalling also influences hypoxia signalling, protease secretion, tumour cell motility and adhesion, and thus can affect the propensity for invasion and metastasis. Therefore, the IGF1R is now an attractive anti-cancer treatment target. IGF1R/CD221 Protein, Human, Recombinant (aa 31-932, His & Avi), Biotinylated is expressed in ...
TMPK-00455	IGF1R/CD221 Protein, Human, Recombinant (His & Avi) MGC142172,IGF-I receptor...	Human	HEK293 Cells
	The type 1 IGF receptor (IGF1R) is a transmembrane tyrosine kinase that is frequently overexpressed by tumours, and mediates proliferation and apoptosis protection. IGF signalling also influences hypoxia signalling, protease secretion, tumour cell motility and adhesion, and thus can affect the propensity for invasion and metastasis. Therefore, the IGF1R is now an attractive anti-cancer treatment target. IGF1R/CD221 Protein, Human, Recombinant (His & Avi) is expressed in HEK293 mammalian cells wi...
TMPK-00658	IGF1R/CD221 Protein, Cynomolgus, Recombinant (His) CD221,IGFR,IGF1R,MGC1421...	Cynomolgus	HEK293 Cells
	The type 1 IGF receptor (IGF1R) is a transmembrane tyrosine kinase that is frequently overexpressed by tumours, and mediates proliferation and apoptosis protection. IGF signalling also influences hypoxia signalling, protease secretion, tumour cell motility and adhesion, and thus can affect the propensity for invasion and metastasis. Therefore, the IGF1R is now an attractive anti-cancer treatment target. IGF1R/CD221 Protein, Cynomolgus, Recombinant (His) is expressed in HEK293 mammalian cells wit...
TMPY-04360	IGF1R/CD221 Protein, Human, Recombinant (His & GST) JTK13,insulin-like growth factor ...	Human	Baculovirus Insect Cells
	IGF1R/CD221 Protein, Human, Recombinant (His & GST) is expressed in Baculovirus insect cells with His and GST tag. The predicted molecular weight is 74.6 kDa and the accession number is P08069.
TMPY-06905	IGF1R/CD221 Protein, Human, Recombinant (His & Avi), Biotinylated CD221,insulin-like growth factor ...	Human	HEK293 Cells
	IGF1R/CD221 Protein, Human, Recombinant (His & Avi), Biotinylated is expressed in HEK293 mammalian cells with His and Avi tag. The predicted molecular weight is 106.14 kDa and the accession number is NP_000866.1.
TMPJ-00781	LR3-IGF-1 Protein, Mouse, Recombinant (His) IGF1,insulin-li...	Mouse	E. coli
	Insulin-like growth factor I (IGF1) belongs to the family of insulin-like growth factors that are structurally homologous to proinsulin. Mouse IGF-I is synthesized as two precursor isoforms with alternate N- and C-terminal propeptides. These isoforms are differentially expressed by various tissues. Mature mouse IGF-I shares 94% and 99% aa sequence identity with human and rat IGF-I, respectively, and exhibits cross-species activity. It shares 60% aa sequence identity with mature mouse IGF-II. IG...

重组蛋白

IGF1R/CD221 Protein, Human, Recombinant (His)

Cat.No: TMPY-00834

Species: Human

Expression System: HEK293 Cells

IGF1R/CD221 Protein, Human, Recombinant (aa 31-932, His & Avi), Biotinylated

Cat.No: TMPK-00456

Species: Human

Expression System: HEK293 Cells

IGF1R/CD221 Protein, Human, Recombinant (His & Avi)

Cat.No: TMPK-00455

Species: Human

Expression System: HEK293 Cells

IGF1R/CD221 Protein, Cynomolgus, Recombinant (His)

Cat.No: TMPK-00658

Species: Cynomolgus

Expression System: HEK293 Cells

IGF1R/CD221 Protein, Human, Recombinant (His & GST)

Cat.No: TMPY-04360

Species: Human

Expression System: Baculovirus Insect Cells

IGF1R/CD221 Protein, Human, Recombinant (His & Avi), Biotinylated

Cat.No: TMPY-06905

Species: Human

Expression System: HEK293 Cells

LR3-IGF-1 Protein, Mouse, Recombinant (His)

Cat.No: TMPJ-00781

Species: Mouse

Expression System: E. coli

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